IVF

Researchers develop tool to help predict fertilization failure
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Researchers in a 2024 study identified what factors were involved in fertilization failure and built a nomogram (calculator) to help predict when this happens, with moderate predictive ability.

Lower cumulative live birth rates with certain forms of endometriosis
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Researchers in a 2024 study found lower cumulative live birth rates in patients with a particular type of endometriosis (DIE and/or ovarian endometrioma) that was diagnosed using transvaginal ultrasound.

Does stress lower IVF success rates?
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Stress may have an impact on IVF success, such as pregnancy rates. In this post we’ll look at what stress is, how it’s measured, and its impact on pregnancy outcomes after IVF, specifically stress measured before IVF starts, during the egg retrieval and during the embryo transfer. We’ll also look at how stress can be alleviated to potentially improve outcomes.

Patients with or without endometriosis have similar live birth rates after PGT-A
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Researchers in a 2023 study found that patients with or without endometriosis have comparable live birth rates after transferring a euploid embryo, although patients may have been surgically treated (a limitation). Endometriosis patients are more likely to produce aneuploid embryos.

POPI-Plus calculator predicts chance of live birth after positive beta-hCG
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Researchers in a 2023 study developed a model to predict the chance of live birth after a positive β-hCG (beta-hCG), using the first measurement and a second one taken 48 hours later.

Explaining Unexplained Infertility through Non-Surgical Endometriosis Diagnosis
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Laparoscopy is the gold standard for diagnosing endometriosis, but other non-surgical tests are showing potential. Here we’ll take a brief look at ReciptivaDx based on the BCL6 protein, the Endotest and DotEndo test based on a miRNA signature, the EMScore which is based on a gene expression signature, and imaging tests like ultrasound and MRI.

ESHRE 2023 guidelines on managing unexplained infertility
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Researchers in 2023 provide evidence-based guidelines for managing patients with unexplained infertility, as prepared by ESHRE.

Meta-analysis examines chance of natural pregnancy following successful IVF
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Researchers in a 2023 study found that about 1 in 5 women achieve a natural pregnancy following a live birth by IVF, with most pregnancies occurring after 2-3 years.

Survey examines the use and attitude of natural cycle FETs in US clinics
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Researchers in a 2023 study share the results of a survey that evaluates the use and attitude of natural cycle FETs in US clinics, which some studies have recently shown can lead to improved pregnancy outcomes compared to medicated FETs.