Studies of sequential euploid embryo transfers suggest that about 63–65% of patients have a live birth after one transfer, increasing to about 83% after two, 92–93% after three, 96% after four, and 98% after five.
Euploid embryos needed for live birth
A 2025 study suggests that most patients with recurrent pregnancy loss who transfer up to 3 euploid embryos go on to have a live birth, though data from later transfers are limited.
In a 2025 study, researchers estimated how many frozen eggs are needed, by age, to reliably yield three euploid blastocysts or achieve one, two or three live births, offering practical guidance for egg freezing patients.
Researchers in a 2024 study found that patients that have 5 consecutive euploid transfers had a cumulative live birth rate of 98.1%, suggesting that most cases of implantation failure are due to the embryo, and that true unexplained RIF occurs in less than 2% of patients.